Hif bnip3
Web1 de set. de 2001 · To additionally check the role of Hif-1α in BNIP3 induction, CHO KA13 and C4.5 cells were subjected to normoxia or hypoxia for 16 h before being analyzed … WebBackground: To explore the roles of HIF1α- and HIF2α-regulated BNIP3 in hypoxia-induced injury of neurons. Methods: The sera of neonates with hypoxic-ischemic encephalopathy …
Hif bnip3
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WebIn contrast, adenovirus-mediated BNIP3 overexpression significantly reversed the decreased mitophagy, and prevented enhanced kidney damage in tubular HIF-1α … WebAnti-HIF-1 alpha antibody [EP1215Y] (ab51608) View more associated products. Overview. Product name. HIF1a + BNIP3 Hypoxia Response Human Flow Cytometry Kit. Detection method. ... BNIP3 readout. HeLa …
Web9 de abr. de 2024 · Nanomaterials are gaining increasing attention as innovative materials in medicine. Among nanomaterials, zinc oxide (ZnO) nanostructures are particularly appealing because of their opto-electrical, antimicrobial, and photochemical properties. Although ZnO is recognized as a safe material and the Zn ion (Zn2+) concentration is strictly regulated … Web17 de mai. de 2024 · BNIP3 depletion halted mitophagy and enforced a PHD2-mediated downregulation of HIF-1α and its glycolytic program both in vitro and in vivo. …
WebUnder normoxia, HIF-1 alpha undergoes hydroxylation at specific prolyl residues which leads to an immediate ubiquitination and subsequent proteasomal degradation of the subunit. In contrast, under hypoxia, HIF … WebWhile hypoxia-inducible factor (HIF) is a major actor in the cell survival response to hypoxia, HIF also is associated with cell death. Several studies implicate the HIF-induced putative …
Web6 de out. de 2024 · HIF is a transcription factor that plays an essential role in the cellular response to low oxygen, orchestrating a metabolic switch that allows cells to survive in this environment. In immunity, infected and inflamed tissues are often hypoxic, and HIF helps immune cells adapt.
WebAlternatively, a variety of mitophagy receptors, including BNIP3L, BNIP3, FUNDC1 ... Greenberg AH, Harris AL. HIF-1-dependent regulation of hypoxic induction of the cell … how to save pumpkin seeds to growWeb21 de mar. de 2024 · BNIP3 (BCL2 Interacting Protein 3) is a Protein Coding gene. Diseases associated with BNIP3 include Hereditary Leiomyomatosis And Renal Cell … north face triclimate inner fleeceWeb3 de set. de 2024 · Highlights Baicalin mitigates H9c2 cell viability loss and apoptosis aroused by hypoxia; Baicalin activates HIF1a/BNIP3 pathway in hypoxia-exposed H9c2 cells; Silencing HIF1α weakens the influences of baicalin on hypoxia-exposed H9c2 cells; Baicalin promotes Nrf2/HO-1 pathway in hypoxia-exposed H9c2 cells; how to save pumpkin seeds to replantWeb1 de set. de 2024 · HIF-1α-BNIP3 signaling pathway contributes to mitophagosome formation in renal tubular cells in confocal assay. Representative immunofluorescence … north face triclimate jacket women\u0027sWeb1 de mai. de 2024 · However, the addition of exogenous disodium-fumarate (Fig EV4E) failed to rescue the levels of HIF-1α in the BNIP3-silenced cells. Together, these data … north face triclimate evolutionWeb31 de jan. de 2024 · BNIP3 mRNA and protein levels are enhanced due to a HRE that occurs in the proximal promoter for bnip3 that binds to the heterodimer of HIF-1, inducing BNIP3 expression [ 14 ]. Hypoxia-induced high-level transcription of bnip3 is mediated by E2F1 releasing from E2F4 and FoxO3 to enhance HIF-1α transcriptional function [ 15, … north face triclimate hyventWeb4 de abr. de 2011 · The data also showed that the activation of autophagy under hypoxic conditions was caused by up-regulated expression of hypoxia-inducible factor-1α (HIF … how to save pumpkin seeds for roasting